multiple system atrophy
noun
: any of several progressive neurodegenerative diseases that are of unknown cause, have an onset usually during middle age and are characterized by a combination of symptoms (as orthostatic hypotension, urinary incontinence, rigidity, and loss of balance) indicative of autonomic dysfunction, parkinsonism, and cerebellar ataxia
—abbreviation MSA
see shy-drager syndrome
Cite this Entry
“Multiple system atrophy.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/multiple%20system%20atrophy. Accessed 4 Nov. 2025.
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